Rickets Osteomalacia (Vitamin D Deficiency)

Vitamin D

Vitamin D is a vitamin that is needed for good health. Unlike other vitamins, vitamin D is not obtained from food. It is mostly made in the skin by the action of sunlight. This is a good thing because most foods contain no or very little vitamin D naturally. Foods that contain vitamin D include:

  • Oily fish (such as sardines, pilchards, herring, trout, tuna, salmon and mackerel).
  • Fortified foods (this means they have vitamin D added to them) such as margarine, some cereals, infant formula milk.

The best dietary source of vitamin D is oily fish and cod liver oil. Egg yolk, liver, and wild mushrooms contain only small quantities of vitamin D.

Vitamin D and sunlight
Ultraviolet B (UVB) rays in sunlight convert cholesterol in the skin into vitamin D. For a fair-skinned person, it is estimated that around 20-30 minutes of sunlight on the face and forearms around the middle of the day 2-3 times a week is sufficient to make enough vitamin D in the summer months. However, for people with darker skin and the elderly, the amount of time needed exposed to sunlight to make enough vitamin D can be much more than this.

Why do we need vitamin D?

A main action of vitamin D is to help calcium and phosphorus in the diet to be absorbed from the gut. Calcium and phosphorus are needed to keep bones healthy and strong. So, vitamin D is important for strong and healthy bones. In addition, vitamin D seems to be important for muscles and general health. There is also some evidence that vitamin D may also help to prevent other diseases such as cancer, diabetes and heart disease.

Who gets vitamin D deficiency?

Vitamin D deficiency means that there is not enough vitamin D in your body. Broadly speaking, this can occur in three situations:

  • The body has an increased need for vitamin D.
  • The body is unable to make enough vitamin D.
  • Not enough vitamin D is being taken in the diet.

Increased need for vitamin D

Growing children, pregnant women, and breast-feeding women need extra vitamin D because it is required for growth. So, vitamin D deficiency is more likely to develop in the following groups of people:

  • Pregnant or breast-feeding women. Vitamin D deficiency is even more likely to develop in women who have had several babies with short gaps between pregnancies. This is because the body’s stores of vitamin D get used up, and there is little time for them to be built up before another pregnancy.
  • Breast-fed babies whose mothers are lacking in vitamin D, or with prolonged breast-feeding, as there is little vitamin D in breast milk. (Note: there are significant advantages to breast-feeding. You should not stop breast-feeding due to concern about vitamin D levels – your baby can simply have vitamin D supplements as drops by mouth.)

Where the body is unable to make enough vitamin D

This can occur for various reasons:

  • People who get very little sunlight on their skin are at risk of vitamin D deficiency.
  • Strict sunscreen use can potentially lead to vitamin D deficiency, particularly if high sun protection factor (SPF) creams (factor 15 or above) are used. Nevertheless, children especially should always be protected from the harmful effect of the sun’s rays and should never be allowed to burn or be exposed to the strongest midday sun.
  • Elderly people have thinner skin than younger people and so are unable to produce as much vitamin D. This leaves older people more at risk of vitamin D deficiency.
  • People who have darker skin. For example, people of African, African-Caribbean and South Asian origin, because their bodies are not able to make as much vitamin D.
  • Some medical conditions can affect the way the body handles vitamin D.
  • Rarely, some people without any other risk factors or diseases become deficient in vitamin D. It is not clear why this occurs. It may be due to a subtle metabolic problem in the way vitamin D is made or absorbed. So, even some otherwise healthy, fair-skinned people who get enough sun exposure can become deficient in vitamin D.
  • Vitamin D deficiency can also occur in people taking certain medicines.

Not enough dietary vitamin D

Vitamin D deficiency is more likely to occur in people who follow a strict vegetarian or vegan diet, or a non-fish-eating diet.

How common is vitamin D deficiency?

It is very common. Most affected people either don’t have any symptoms, or have tiredness or vague aches and pains, and are unaware of the problem.

Symptoms of vitamin D deficiency

Many people have no symptoms, or may complain of only vague ones such as tiredness or general aches. Because symptoms of vitamin D deficiency are often very nonspecific or vague, the problem is often missed. The diagnosis is more easily reached in severe deficiencies with some of the classical (typical) symptoms and bone deformities.

Symptoms in babies and children

  • Babies with severe vitamin D deficiency can get muscle spasms (cramps), seizures and breathing difficulties. These problems are related to consequent low levels of calcium.
  • Children with severe deficiency may have soft skull or leg bones. Their legs may look curved (bow-legged). They may also complain of bone pains, often in the legs, and muscle pains or muscle weakness. This condition is known as rickets.
  • Poor growth. Height is usually affected more than weight. Affected children might be reluctant to start walking.
  • Tooth delay. Children with vitamin D deficiency may be late teething as the development of the milk teeth has been affected.
  • Irritability in children can be due to vitamin D deficiency.
  • Children with vitamin D deficiency are more prone to infections. Breathing (respiratory) symptoms can occur in severe cases. Breathing can be affected because of weak chest muscles and a soft ribcage.
  • When rickets if very severe, it can cause low levels of calcium in the blood. This can lead to muscle cramps (spasms), fits (seizures) and breathing difficulties. These need urgent hospital treatment.
  • Rarely, an extremely low vitamin D level can cause weakness of the heart muscle (cardiomyopathy).

Symptoms in adults

  • Some people complain of a general tiredness, vague aches and pains and a general sense of not being well.
  • In more severe deficiency (known as osteomalacia), there may be more severe pain and also weakness. Muscle weakness may cause difficulty in climbing stairs or getting up from the floor or a low chair, or can lead to the person walking with a waddling pattern.
  • Bones can feel painful to moderate pressure (often more noticeable in the ribs or shin bones). Not uncommonly, people have a hairline fracture in the bone which is causing tenderness and pain. Bone pain often also occurs in the lower back, hips, pelvis, thighs and feet.

Diagnosis of vitamin D deficiency

It may be suspected from your medical history, symptoms, or lifestyle. A simple blood test for vitamin D level can make the diagnosis. Blood tests for calcium and phosphate levels and liver function may also show changes linked to a low level of vitamin D. Sometimes, a wrist X-ray is done for a child. This can assess how severe the problem is by looking for changes in the wrist bones.

Treatment for vitamin D deficiency

The treatment is to take vitamin D supplements. Vitamin D can be given as an injection or as a medicine (liquid or tablets). The dose, and best treatment schedule, depends on the patients situation, age, severity of the deficiency, etc.

Cautions when taking vitamin D supplements

Care is needed with vitamin D supplements in certain situations:

  • If digoxin is being taken. In this situation, high doses of vitamin D should be avoided, and digoxin will need monitoring more closely.
  • In case of medical conditions such as: kidney stones, some types of kidney disease, liver disease or hormonal disease. Specialist advice may be needed.
  • Vitamin D should not be taken by people who have high calcium levels or certain types of cancer.

Multivitamins are not suitable for long-term high-dose treatment because the vitamin A they also contain can be harmful in large amounts.

Side-effects from vitamin D supplements

It is very unusual to get side-effects from vitamin D if taken in the prescribed dose. However, very high doses can raise calcium levels in the blood. This would cause symptoms such as thirst, passing a lot of urine, nausea or vomiting, dizziness and headaches. If these symptoms develop, a doctor should be seen promptly, so that calcium levels can be checked with a blood test. Some guidelines advise that people taking high vitamin D doses should have their calcium levels checked during the first few weeks. In practice, this is not usually done unless symptoms of a high blood calcium level develop.

What is the outlook (prognosis)?

The outlook is usually excellent. Both the vitamin levels and the symptoms generally respond well to treatment. However, it can take time (months) for bones to recover and symptoms such as pain to get better or improve.

The complications of severe deficiency have been mentioned. Rickets can occur in children, and osteomalacia in adults. These diseases affect the strength and appearance of bones, and can lead to permanent bone deformities if untreated or if treatment is delayed.

Vitamin D has been linked to other diseases. In recent years there have been associations with conditions such as cancer, heart disease, infectious disorders, autoimmune disease and diabetes. This does not mean that all people with vitamin D deficiency will get these problems. In these cases, vitamin D is thought to be just one factor.


Most people who are treated for vitamin D deficiency will need to be reviewed a few weeks or months after starting treatment, depending on how severe their symptoms are. A further review after one year is advised.

Be the first to comment

Leave a Reply

Your email address will not be published.